Conolidine’s analgesic outcomes stem from its conversation with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors while in the central nervous process, conolidine modulates alternate molecular targets. A Science Advancements study identified that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availab... https://redhotbookmarks.com/story20559375/the-ultimate-guide-to-alternative-natural-pain-relief-to-replace-traditional-painkillers