Weak/Comprehensive Metabolizers, CYP2D6 The formation of your Energetic metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Around seven% of the populace has minimized activity from the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme procedure. These people today are “very poor metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amongst other https://edsgerf034hbw0.buscawiki.com/user