Abstract Background As a chronic mountain sickness(CMS) with the highest incidence and the greatest harm. the pathogenesis of high altitude polycythemia (HAPC) is still not fully understood. Methods 37 HAPC patients and 42 healthy subjects were selected from plateau. and peripheral venous blood samples were collected for transcriptome sequencing on Illumina NovaSeq platform. https://www.ngetikin.com/limited-save-Apple-iPhone-14-Pro-Clear-Case-with-MagSafe-save-big/