Pentobarbital will decrease the level or effect of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers reduces plasma concentration of abemaciclib and its metabolites. Corticosteroids: Barbiturates appear to enhance the metabolism of exogenous corticosteroids probably through the... https://andredinpt.blogoscience.com/36209759/un-arma-secreta-para-es-el-pentobarbital-sódico-una-droga-controlada